Development, Validation, and Application of a Simple and Rugged HPLC Method for Boswellic Acids for a Comparative Study of Their Abundance in Different Species of Boswellia Gum Resins

The resin of Boswellia plant species has been used since ancient times for its several bio-active curative effects. In modern times, extracts this are still widely commercialized on the food supplements and nutraceuticals market. Nowadays legislation botanical increasing demand their safety traceability setting new standards chemical characterization. work we present an easy, feasible rugged HPLC-UV-based approach quantitation boswellic acids in food-supplement-grade species. This method can be quality control purposes as well studying differences regional origin, years harvesting species-related differences. employs a C18 (3 × 150 mm, 3 µm) analytical HPLC column, separation is carried out through gradient acetonitrile/water with 0.1% formic acid. was validated following ICH guidelines to quantitate different samples commercial carteri serrata together other from unknown six known were identified quantified all analyzed samples. results build multivariate model graphically appreciate difference clustering. then augmented by adding further data belonging obtained another scientific publications increase number studied